We know that probiotics are live active cultures that when administered in adequate amounts confer a health benefit to the host. But what essentially makes a probiotic a probiotic? To be labeled as a probiotic, the product should be capable of surviving the irritant effects of both the stomach acid and bile to arrive at their destination in the colon where they exert their effects.
How do probiotics work?
The probiotics work through a number of mechanisms to strengthen our immune defenses and prevent us from sickness.
It is recognized for decades that the restoration of the balance in the microbial gut population is crucial for our health, and its disruption precipitates several GI and non-GI disease states. Depending upon the duration of their effects, probiotics can be classified as transient versus colonizing. Transient probiotics travel to the gut but are incapable of making a permanent home in the microbiome. They work as long as they are taken. In contrast, the colonizing probiotics (as the name implies) tend to colonize in the gut permanently; their effects last even after discontinuing them. Both kinds of probiotics stick to the gut wall to fend off the harmful invaders from adhering and exerting their deleterious effects. They block the growth of the bad pathogens and therefore, serve to boost the immune defenses both locally within and outside the gut.