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Ingredients
All ingredients are sourced from renewable and sustainable sources
Probiotic Ingredients

Lactobacillus reuteri NCIMB 30242
3.5 Billion AFU/capsule
Our primary ingredient is our unique probiotic strain which has been through rigorous clinical trials performed by independent labs and researchers and published in 7 peer-reviewed scientific papers
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Other Ingredients
In each capsule:
- Microcrystalline cellulose
- Silicone dioxide
- Magnesium stearate
- Vegetable capsule (hypromellose, titanium dioxide)
Prebiotic Ingredients

scFOS
600mg/tablet
Short-chain fructooligosaccharides (scFOS) are natural dietary fibers that belong to the fructans family and are proven to aid in healthy bacterial growth and prevent the colonization and growth of pathogenic gut bacteria.
Other Ingredients
In each capsule:
- Microcrystalline cellulose
- Dicalcium phosphate
- Stearic acid
- Magnesium stearate
- Croscarmellose sodium
- Silicon dioxide
Microbiome Plus+ Pre and Probiotic Supplements Compared to Other Probiotics
|
Microbiome Plus+ pre and probiotics |
Brand A |
Brand B |
Clinically researched pre and probiotic combination |
✔ |
✘ |
✘ |
GRAS status |
✔ |
✔ |
✘ |
CFU count per strain per capsule |
3.5B |
2.3B |
2.5B |
Prebiotic fiber dosage per capsule/tablet |
600 mg |
200 mg |
5mg |
Acid-resistant capsule |
✔ |
✔ |
✘ |
Designed for survivability |
✔ |
✘ |
✘ |
Dairy free, gluten free, and soy free |
✔ |
✘ |
✔ |
Shelf-stable bottle |
✔ |
✔ |
✔ |
Supports already healthy vitamin D levels |
✔ |
✘ |
✘ |
Supports already normal cholesterol |
✔ |
✘ |
✘ |
Encourages gut microbiome diversity |
✔ |
✔ |
✔ |
Histamine-release free |
✔ |
✘ |
✘ |
IBS safe |
✔ |
✘ |
✘ |

Take one probiotic capsule and one prebiotic tablet twice daily with meals or as directed by a physician.
Take one probiotic capsule and one prebiotic tablet twice daily with meals or as directed by a physician.
Recommended By Doctors

"I have been using MicroBiome Plus for several years. It has greatly benefitted my patients with gut problems and those with cardio metabolic issues as well.
— Dr. Deanna M. Cherrone, Natural Health and Healing Clinic
Know what you’re Getting
RIGOROUSLY SELECTED ACTIVE INGREDIENTS: Whereas many companies use clinically untested blends of many probiotics and prebiotics just to achieve a high CFU count, we stick to what we know. We selected only two active ingredients that work both individually and together.
THE POWER OF SYNBIOTICS: Our science-based and clinically proven synbiotic formula relies on synergy and supports your overall health and well-being. Synbiotics are supplements that combine the power of probiotics and prebiotics, increasing each other’s benefits in the form of synergism.
About L. Reuteri NCIMB 30242 Probiotic (LRC)
The probiotic in Microbiome Plus+ Gastrointestinal has been shown in clinical trials to help support normal inflammatory response in addition to supporting digestive health.*
- L. reuteri NCIMB 30242 is the only probiotic shown to help maintain healthy bile metabolism*
- By promoting healthy bile metabolism L. reuteri NCIMB 30242 has multiple health benefits*
- L. reuteri NCIMB 30242 promotes digestive health and maintains a healthy digestive system*
- Helps maintain healthy levels of cholesterol – (Lowers LDL Cholesterol)*
- Helps maintain healthy levels of vitamin D*
- Supports normal inflammatory response*

Microbiome Plus+ Pre and Probiotics Benefits
NORMAL CHOLESTEROL & HEART HEALTH: Normal cholesterol levels are important for your cardiovascular system. Our Microbiome Plus+ Lactobacillus Reuteri NCIMB 30242 probiotic provides clinically tested natural support for your already normal total and LDL cholesterol levels. It also helps sustain healthy levels of already normal C-reactive protein, apolipoprotein B-100, fibrinogen, and plant sterols. Normal levels of these factors support your heart, blood vessels, and blood clotting.
VITAMIN D: Our combo contains the only clinically researched probiotic strain that supports keeping already normal vitamin D blood levels in check. Normal vitamin D levels help build and maintain strong bones, absorb calcium in the gut, and balance immune health.
IMMUNE SYSTEM SUPPORT: 80% of your immune system in your gut. By encouraging a healthy gut microbiome and already normal vitamin D levels, our probiotics and prebiotics contribute to optimal immune system function in healthy people.
WEIGHT CONTROL, BILE & COLON HEALTH: Our pre and probiotics help maintain a healthy gut lining, normal fat digestion, and optimal metabolism by freeing up bile acids. Normal levels of free bile acids may help strengthen the intestinal lining. A diverse microbiome supports the body in maintaining insulin sensitivity and healthy weight, along with diet and exercise.
DIGESTION, STOMACH & BLOATING RELIEF: Microbiome Plus+ probiotics and prebiotics assist good digestion, gastrointestinal health, and gut microbiome diversity. Gut microbiome dysbiosis has been linked with stomach discomfort, pain, and bloating.
BOWEL MOVEMENT SUPPORT: Our pre and probiotics work with your gut to encourage healthy bowel movements, optimal bowel function, and passage of stools. By helping maintain a strong intestinal lining, Microbiome Plus+ Lactobacillus Reuteri NCIMB 30242 supports the body in preventing harmful organisms from crossing from the gut into the bloodstream. Prebiotics enhance its benefits.
IBS RELIEF: Our combo is IBS safe. Lactobacillus Reuteri NCIMB 30242 supports normal bile acid levels, which encourages a balanced gut ratio of Firmicutes to Bacteroidetes in healthy people. People with IBD often have an imbalanced Firmicutes to Bacteroidetes ratio, according to studies. Plus, we chose scFOS fiber because it was clinically researched for supporting microbiome health in people with IBS.
Microbiome Plus+ prebiotics and probiotics are manufactured in GMP-certified US facilities, rooted in science, and backed by many clinical trials (Read the studies here: Jones et al., 2011, Jones & Prakash, 2012; Jones et al., 2013, Jones et al., 2013; Martoni et al., 2015; Jones et al., 2011; Jones et al, 2012).
Prebiotics & Probiotics for Women and Men
Microbiome Plus+ Gastrointestinal Combo supports both men’s and women’s health with just two select active ingredients: probiotic L. Reuteri NCIMB 30242 and prebiotic scFOS fiber.
PRE AND PROBIOTICS FOR WOMEN: Our prebiotics and probiotics support women’s digestive and overall health. Lactobacillus Reuteri probiotics are a normal part of a healthy vaginal, breast milk, and gut flora in women. Prebiotic fiber also supports weight control, a sense of fullness, and regular bowel movements. Plus, a healthy microbiome helps the body maintain a healthy vaginal pH balance.
PRE AND PROBIOTICS FOR MEN: Our pre and probiotic combo supports men’s health by contributing to normal gastrointestinal, metabolic function, sugar control, and overall health. Lactobacillus reuteri probiotics support male fertility and testosterone levels already in the normal range in healthy men. Fiber supports normal bowel movements, aids in achieving a healthy weight, and contributes to prostate health.
More Information
Ingredients
PROBIOTIC Capsule: Lactobacillus reuteri NCIMB 30242 3.5 billion CFU. Other Ingredients: microcrystalline cellulose, silicon dioxide, magnesium stearate, vegetable capsule (hypromellose, titanium dioxide). PREBIOTIC scFOS Tablet: scFOS (Short-chain fructo oligosaccharides) 600mg. Other Ingredients: microcrystalline cellulose, dicalcium phosphate, stearic acid, magnesium stearate, croscarmellose sodium and silicon dioxide.
About Microbiome Plus+ Gastrointestinal - Probiotic & Prebiotic Combo
Microbiome Plus+ Gastrointestinal Probiotic and Prebiotic Combo is a powerful supplement supported by rigorous scientific analysis. L. reuteri NCIMB 30242 is one of the few probiotics given GRAS (Generally Recognized as Safe) status, our prebiotic fiber scFOS is designed to boost the effectiveness of our probiotic in a synbiotic combination that synergistically promotes gastrointestinal health.
Faq's
- Do Microbiome Plus+ probiotics need to be refrigerated?
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What are the ingredients in these products?
PROBIOTIC CAPSULE INGREDIENTS:Lactobacillus reuteri NCIMB 30242 3.5 billion CFU per capsule. Other ingredients:microcrystalline cellulose, silicon dioxide, magnesium stearate, vegetable capsule (hypromellose, titanium dioxide). PREBIOTIC TABLET INGREDIENTS:scFOS (Short-chain fructooligosaccharides) 600mg per tablet.
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Does this product contain scFOS?
Yes, our prebiotic tablets contain scFOS.
Our probiotic capsules do not contain scFOS.
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Should I take this product or the probiotic only?
Our Microbiome Plus+ Gastrointestinal Combo (Probiotic L. Reuteri NCIMB 30242 & Prebiotic scFOS Fiber) may be more suitable for people who don’t have an issue with FODMAPs. Prebiotics act in synergy with probiotics. You can get it here.
The probiotic without the combo (Microbiome Plus+ Lactobacillus Reuteri NCIMB 30242) is without short-chain fructooligosaccharides (scFOS).
The probiotic included in our combo was researched in people with IBS, so it’s considered to be “IBS safe.”
Nonetheless, FODMAPs tend to cause problems in some people with irritable bowel syndrome (IBS).
The probiotic only (without the prebiotic) may be more suitable for people who don’t tolerate FODMAPs (fermentable oligo-, di-, mono-saccharides and polyols).
Microbiome Plus+ Prebiotic scFOS Fiber is also available as a separate product here. You can try adding it to the probiotic if you’re not sure what’s right for you.
If you have IBS or don’t tolerate FODMAPs, please talk to a doctor. Have in mind that this product is not a treatment for your condition.
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Why do Microbiome Plus+ probiotics contain hydroxypropyl methylcellulose (HPMC)?
Hydroxypropyl methylcellulose (HPMC) is a food-grade, plant-based polymer. It’s used to encapsulate the probiotic in a vegan delayed-release capsule. This innovative technology helps live probiotics in our formulation resist stomach acid and reach the colon. Without HPMC, live probiotics would be killed by stomach acid.
Read more about our delayed-release technology here. -
Why do Microbiome Plus+ probiotics contain gellan gum? Is gellan gum safe?
Gellan gum is used as part of our microencapsulation technology. It’s added to enhance the viability of probiotics.
Gellan gum has been thoroughly researched for enhancing the delivery of live probiotics in various formulations. Please look up “Microencapsulation Improved Probiotics Survival During Gastric Transit.”
Gellan gum has been extensively studied, tested, and proven to be safe for use in food for over 30 years. Scientists even tested the safety of gellan gum mega doses that would never be used in food (pounds in one meal) and concluded that it was non-toxic.
Gellan gum is made using bacteria found in nature to ferment nutrients. It’s commonly added to many foods in small amounts (to create gels and add texture).
As with many components of food, such as lactose or gluten, some people may have individual or unique sensitivities.
The amount of gellan gum in our probiotic formulation is lower than that found in common foods.
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Do Microbiome Plus+ probiotics contain live cultures?
Yes, our probiotics contain live cultures. They are third-party tested for quality.
Each capsule contains 3.5×10⁹ CFU of Lactobacillus Reuteri NCIMB 30242.
Independent peer-reviewed research has also validated this. -
Can I ferment milk with this probiotic?
This is possible, but you would need to follow careful steps to start the fermentation process.
If you tried adding probiotic powder to milk and didn’t see any change, it’s not because the product doesn’t contain live bacteria. Not all Lactobacillus probiotics grow in milk the same way, and there are various scientific studies dedicated to the topic.
Our strain was specifically selected, developed, and grown in the lab without milk. That means it may need time to adapt to a dairy environment. Scientists tested this out. They showed that Lactobacillus reuteri NCIMB 30242 can ferment milk along with a yogurt starter, but its growth was limited.
For this reason, we recommend taking our probiotics as capsules. This ensures that you’ll get the dosage and formulation that was clinically researched.
But if you’re really into yogurt making, give this topic some in-depth research. You may want to Google “how to make lactobacillus reuteri yogurt” and run your own experiments. We can’t guarantee any results.
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Who can benefit from Microbiome Plus+ Gastrointestinal Combo Probiotic L. Reuteri NCIMB 30242 & Prebiotic scFOS Fiber?
Our prebiotic and probiotic combo is a good choice for adults looking to naturally support digestion, colon health, and LDL and total cholesterol levels that are already within the normal range.
Also, healthy people who are looking to maintain immune health and vitamin D levels that are already in the normal range may benefit from our combo.
Microbiome Plus+ probiotics are meant for both men and women who want to support their gut microbiome, weight management, nutrient balance along with a healthy diet, and overall well-being.
The synbiotic combination in our formula is safe for most people with IBS, but check with your doctor if you’re not sure.
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Is this product safe for everyone?
Microbiome Plus+ Lactobacillus Reuteri NCIMB 30242 and scFOS are safe to consume daily for most people. Our probiotic has been granted Generally Recognized as Safe (GRAS) status by the U.S. Food and Drug Administration.
L. reuteri probiotics have a long history of safe use in traditional fermented foods.
Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any other dietary supplement. Do not take this supplement if you are allergic to any of the listed ingredients.
These statements have not been evaluated by the U.S. Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.