Microbiome Plus+ develops products using the science of the microbiome to deliver ingredients that have been proven to support digestive functions and overall health.

We are dedicated to providing advanced digestive health supplements that are backed by science. Our probiotic L. reuteri NCIMB 30242 is one of the few probiotic strains granted GRAS status and has been shown in several human clinical trials to improve cardiovascular and other health markers.

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Disclaimer: This page provides an overview of the research on the probiotic strain in our supplements. It is for informational purposes only and is not meant to provide any medical advice. Please talk to your doctor about your health concerns and consult them before taking any supplements or making changes to your supplement regime.

The clinical studies below were performed by independent laboratories focused on health science and digestive research:

Supports Healthy Cholesterol Already in the Normal Range

Microbiome Plus+ Probiotic NCIMB 30242 LRC is very unique because it is considered a “heart healthy probiotic” and it is the only probiotic that has been clinically proven to support healthy LDL cholesterol already in the normal range.

Cholesterol lowering and inhibition of sterol absorption by Lactobacillus reuteri NCIMB 30242: a randomized controlled trial.

Supports Healthy Already Normal Vitamin D Levels

Low serum 25-hydroxyvitamin D is a risk factor for osteoporosis, cardiovascular disease, diabetes, and cancer. Many people suffer from vitamin D deficiency, and our unique probiotic has been shown to support already normal vitamin D levels.

Probiotic L. reuteri NCIMB 30242 increases mean circulating 25-hydroxyvitamin D: a post hoc analysis of a randomized controlled trial.

Improves Gastrointestinal Health

Microbiome Plus+ Probiotic NCIMB 30242 LRC has been proven in a human clinical trial to considerably improve gastrointestinal health. Subjects in the randomized, double-blind, placebo-controlled study reported significant GI health improvement.

Improvement of gastrointestinal health status in subjects consuming Lactobacillus reuteri NCIMB 30242 capsules: a post-hoc analysis of a randomized controlled trial.

Maintains Healthy Bile Metabolism

Microbiome Plus+ Probiotic NCIMB 30242 LRC enhances the production of an enzyme called bile salt hydrolase by promoting a healthy gut microbiome, which facilitates healthy bile metabolism. Bile is involved in digestion of food, absorption of fat, absorption of cholesterol, removal of cholesterol from the body, production of hormones, absorption of vitamins, production of vitamins, and act on receptors found to be essential in weight management and glucose metabolism.

Changes in bile acids, FGF-19 and sterol absorption in response to bile salt hydrolase active L. reuteri NCIMB 30242.

Developed by Doctors

Microbiome Plus+ Gastrointestinal Probiotic and Prebiotic Combo is a powerful supplement supported by rigorous scientific analysis. Many clinical studies show the benefits, safety, and effectiveness of L. reuteri NCIMB 30242.

* These statements have not been evaluated by the U.S. Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Please consult your physician before implementing any new diet, exercise, and dietary supplement programs, especially if you have preexisting medical conditions or are taking prescribed medications.