Recommended By Doctors

"I have been using MicroBiome Plus for several years. It has greatly benefitted my patients with gut problems and those with cardio metabolic issues as well.
— Dr. Deanna M. Cherrone, Natural Health and Healing Clinic
Prebiotics & Probiotics for Women and Men
PRE AND PROBIOTICS FOR WOMEN
Our prebiotics and probiotics support women’s digestive and overall health. Lactobacillus Reuteri probiotics are a normal part of a healthy vaginal, breast milk, and gut flora in women. Prebiotic fiber also supports weight control, a sense of fullness, and regular bowel movements. Plus, a healthy microbiome helps the body maintain a healthy vaginal pH balance.
PRE AND PROBIOTICS FOR MEN
Our pre and probiotic combo supports men’s health by contributing to normal gastrointestinal, metabolic function, sugar control, and overall health. Lactobacillus reuteri probiotics support male fertility and testosterone levels already in the normal range in healthy men. Fiber supports normal bowel movements, aids in achieving a healthy weight, and contributes to prostate health.
RIGOROUSLY SELECTED ACTIVE INGREDIENTS
Whereas many companies use clinically untested blends of many probiotics and prebiotics just to achieve a high CFU count, we stick to what we know. We selected only two active ingredients that work both individually and together: probiotic L. Reuteri NCIMB 30242 and prebiotic scFOS fiber. Microbiome Plus+ Gastrointestinal Combo supports both men’s and women’s health.
Benefits of Our Probiotic and Prebiotic Combo
NORMAL CHOLESTEROL
Normal cholesterol levels are important for your cardiovascular system. Our Microbiome Plus+ Lactobacillus Reuteri NCIMB 30242 probiotic provides clinically tested natural support for your already normal total and LDL cholesterol levels.

HEART HEALTH
Our probiotic strain It also helps sustain healthy levels of already normal C-reactive protein, apolipoprotein B-100, fibrinogen, and plant sterols. Normal levels of these factors support your heart, blood vessels, and blood clotting.
VITAMIN D
Our combo contains the only clinically researched probiotic strain that supports keeping already normal vitamin D blood levels in check. Normal vitamin D levels help build and maintain strong bones, absorb calcium in the gut, and balance immune health.
DIGESTION, STOMACH & BLOATING RELIEF
Microbiome Plus+ probiotics and prebiotics assist good digestion, gastrointestinal health, and gut microbiome diversity. Gut microbiome dysbiosis has been linked with stomach discomfort, pain, and bloating.
DELAYED RELEASE CAPS
With low-moisture content, our delayed release capsules help protect our probiotic against the harsh stomach environment. This enables live probiotics to pass safely through the stomach, ensuring delivery of intact bacteria to your system. Read More

THE POWER OF SYNBIOTICS
Our science-based and clinically proven synbiotic formula relies on synergy and supports your overall health and well-being. Synbiotics are supplements that combine the power of probiotics and prebiotics, increasing each other’s benefits in the form of synergism.
MOOD, ENERGY & WELL-BEING
A healthy gut microbiome supports nutrient absorption, general wellbeing, mood, and cognitive function. Fatigue, irritability, and poor motivation may be signs of a nutrient deficiency. Please discuss your symptoms with your doctor. Prebiotics and probiotics encourage a healthy microbiome and optimize nutrient breakdown and absorption.
DEVELOPED BY DOCTORS
When it comes to the health effects and quality of our products, we leave no room for guessing. Microbiome Plus+ prebiotics and probiotics are manufactured in GMP-certified US facilities, rooted in science, and backed by many clinical trials . Read ALL Studies Here

Take one probiotic capsule and one prebiotic tablet twice daily with meals or as directed by a physician.
Take one probiotic capsule and one prebiotic tablet twice daily with meals or as directed by a physician.
A Science-Backed Probiotic with Prebiotic Fiber
- GRAS: Our L. reuteri NCIMB 30242 is among the few probiotic strains granted Generally Recognized As Safe (GRAS) status by the U.S. Food and Drug Administration. It’s suitable for adult men and women of all ages.
- 7 BILLION CFU DAILY PROBIOTIC DOSE: taken as two capsules per day, formulated to restore the gut microbiome and bile acid balance.
- 1200 MG DAILY PREBIOTIC DOSE: taken as two tablets per day, formulated to boost probiotic effects and microbiome diversity in your colon.
- 28-days supply in each bottle
- NO REFRIGERATION REQUIRED: Both our probiotic and prebiotic is 100% shelf stable. In fact, our probiotic is designed for survivability. No need to keep it in the fridge—you can take it with you wherever you go. It provides live bacteria until the expiry date.
- NO HISTAMINE RELEASE: Unlike many other strains, L. reuteri NCIMB 30242 didn’t release biogenic amines like histamine, tyramine, putrescine, and cadaverine in lab tests.
- FREE OF ALLERGENS: Our probiotic doesn’t contain gluten, soy, corn, milk, egg, wheat, peanuts, shellfish, or preservatives.
- VEGAN and NON-GMO, from renewable and sustainable sources.
- DEVELOPED BY DOCTORS AND SCIENTISTS, extensively tested in cellular and clinical studies.
- MADE IN USA, manufactured in facilities following Good Manufacturing Practice (GMP) standards.
- THIRD-PARTY TESTED: Our pre and probiotic supplements are routinely third-party tested for potency, heavy metals, and micros. When you purchase our products, you know you’re getting a safe, effective, clean formulation.

What’s inside?
PROBIOTIC CAPSULES
Each capsule contains 3.5 billion CFU L. Reuteri NCIMB 30242 and starts acting only once it reaches your colon thanks to our delayed-release technology..
PREBIOTIC TABLETS
Each prebiotic tablet contains 600 mg of concentrated short-chain fructooligosaccharides (scFOS), non-digestive fiber that supports the growth of a diverse gut microbiome in your colon.
Now you can support your health by taking two science-backed ingredients only: one probiotic, one prebiotic. Clinically researched dosage and formulation. You know exactly what you’re getting. No need to experiment with untested mixtures and dosages of dozens of probiotic strains and prebiotics you don’t tolerate.
More Information
- Do Microbiome Plus+ probiotics need to be refrigerated?
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What are the ingredients in the prebiotic and probiotic supplements?
PROBIOTIC CAPSULE INGREDIENTS:
Lactobacillus reuteri NCIMB 30242 3.5 billion CFU per capsule.Other ingredients: microcrystalline cellulose, silicon dioxide, magnesium stearate, vegetable capsule (hypromellose, titanium dioxide).
PREBIOTIC TABLET INGREDIENTS:
scFOS (Short-chain fructooligosaccharides) 600mg per tablet.Other Ingredients: microcrystalline cellulose, dicalcium phosphate, stearic acid, magnesium stearate, croscarmellose sodium and silicon dioxide.
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Does this product contain scFOS?
Onlu our prebiotic tablets contain scFOS.
Our probiotic capsules do not contain scFOS.
Other products do not contain scFOS.
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Should I take the combo or the probiotic only?
Our Microbiome Plus+ Gastrointestinal Combo (Probiotic L. Reuteri NCIMB 30242 & Prebiotic scFOS Fiber) may be more suitable for people who don’t have an issue with FODMAPs. Prebiotics act in synergy with probiotics.
The probiotic without the combo (Microbiome Plus+ Lactobacillus Reuteri NCIMB 30242) is without short-chain fructooligosaccharides (scFOS).
The probiotic included in our combo was researched in people with IBS, so it’s considered to be “IBS safe.”
Nonetheless, FODMAPs tend to cause problems in some people with irritable bowel syndrome (IBS).
The probiotic only (without the prebiotic) may be more suitable for people who don’t tolerate FODMAPs (fermentable oligo-, di-, mono-saccharides and polyols).
Microbiome Plus+ Prebiotic scFOS Fiber is also available as a separate product. You can try adding it to the probiotic if you’re not sure what’s right for you.
If you have IBS or don’t tolerate FODMAPs, please talk to a doctor. Have in mind that this product is not a treatment for your condition.
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Why do Microbiome Plus+ probiotics contain hydroxypropyl methylcellulose (HPMC)?
Hydroxypropyl methylcellulose (HPMC) is a food-grade, plant-based polymer. It’s used to encapsulate the probiotic in a vegan delayed-release capsule. This innovative technology helps live probiotics in our formulation resist stomach acid and reach the colon. Without HPMC, live probiotics would be killed by stomach acid.
Read more about our delayed-release technology here.
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Why do Microbiome Plus+ probiotics contain gellan gum? Is gellan gum safe?
Gellan gum is used as part of our microencapsulation technology. It’s added to enhance the viability of probiotics.
Gellan gum has been thoroughly researched for enhancing the delivery of live probiotics in various formulations. Please look up “Microencapsulation Improved Probiotics Survival During Gastric Transit.”
Gellan gum has been extensively studied, tested, and proven to be safe for use in food for over 30 years. Scientists even tested the safety of gellan gum mega doses that would never be used in food (pounds in one meal) and concluded that it was non-toxic.
Gellan gum is made using bacteria found in nature to ferment nutrients. It’s commonly added to many foods in small amounts (to create gels and add texture).
As with many components of food, such as lactose or gluten, some people may have individual or unique sensitivities.
The amount of gellan gum in our probiotic formulation is lower than that found in common foods.
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Do Microbiome Plus+ probiotics contain live cultures?
Yes, our probiotics contain live cultures. They are third-party tested for quality.
Each capsule contains 3.5×10⁹ CFU of Lactobacillus Reuteri NCIMB 30242.
Independent peer-reviewed research has also validated this.
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Can I ferment milk with this probiotic?
This is possible, but you would need to follow careful steps to start the fermentation process.
If you tried adding probiotic powder to milk and didn’t see any change, it’s not because the product doesn’t contain live bacteria. Not all Lactobacillus probiotics grow in milk the same way, and there are various scientific studies dedicated to the topic.
Our strain was specifically selected, developed, and grown in the lab without milk. That means it may need time to adapt to a dairy environment. Scientists tested this out. They showed that Lactobacillus reuteri NCIMB 30242 can ferment milk along with a yogurt starter, but its growth was limited.
For this reason, we recommend taking our probiotics as capsules. This ensures that you’ll get the dosage and formulation that was clinically researched.
But if you’re really into yogurt making, give this topic some in-depth research. You may want to Google “how to make lactobacillus reuteri yogurt” and run your own experiments. We can’t guarantee any results.
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Who can benefit from Microbiome Plus+ probiotics?
Our prebiotic and probiotics are a good choice for adults looking to naturally support digestion, colon health, and LDL and total cholesterol levels that are already within the normal range.
Also, healthy people who are looking to maintain immune health and vitamin D levels that are already in the normal range may benefit from our combo or standalone probiotic.
Microbiome Plus+ probiotics are meant for both men and women who want to support their gut microbiome, weight management, nutrient balance along with a healthy diet, and overall well-being.
The synbiotic combination in our formula is safe for most people with IBS, but check with your doctor if you’re not sure.
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Is this product safe for everyone?
Microbiome Plus+ Lactobacillus Reuteri NCIMB 30242 and scFOS are safe to consume daily for most people. Our probiotic has been granted Recognized as Safe (GRAS) status by the U.S. Food and Drug Administration.
L. reuteri probiotics have a long history of safe use in traditional fermented foods.
Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any other dietary supplement. Do not take this supplement if you are allergic to any of the listed ingredients.
These statements have not been evaluated by the U.S. Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.