Recommended By Doctors

"I have been using MicroBiome Plus for several years. It has greatly benefitted my patients with gut problems and those with cardio metabolic issues as well.
— Dr. Deanna M. Cherrone, Natural Health and Healing Clinic

Take one capsule twice daily with meals or as directed by a physician.
Take one capsule twice daily with meals or as directed by a physician.
Benefits of Microbiome Plus+ Heart-Healthy Probiotics
NORMAL CHOLESTEROL
Maintaining normal cholesterol levels is important for cardiovascular health. Our Microbiome Plus+ Lactobacillus Reuteri NCIMB 30242 probiotic provides clinically tested natural support for your already normal total and LDL cholesterol levels. It’s for both men and women who want to maintain a healthy heart and circulation.
HEART HEALTH & BLOOD FLOW
Microbiome Plus+ Lactobacillus Reuteri NCIMB 30242 helps sustain healthy levels of already normal C-reactive protein and apolipoprotein B-100. These factors support heart and blood vessel health. Plus, our probiotic encourages already normal fibrinogen, a protein involved in healthy blood clotting and blood flow.
VITAMIN D
Microbiome Plus+ Lactobacillus Reuteri NCIMB 30242 is the only clinically researched probiotic strain that supports keeping already normal vitamin D blood levels in check. Normal vitamin D levels help build and maintain strong bones, absorb calcium in the gut, and balance immune health.
METABOLISM, GUT & BILE HEALTH:
Our Microbiome Plus+ probiotic assists good digestion, gastrointestinal health, and gut microbiome diversity. It also helps maintain a healthy gut lining, normal fat digestion, and optimal metabolism by freeing up bile acids. Normal levels of free bile acids may help strengthen the intestinal lining. A diverse microbiome supports the body in maintaining insulin sensitivity and healthy weight, along with diet and exercise.
IMMUNE SYSTEM HEALTH
80% of your immune system in your gut. By encouraging a healthy gut microbiome and already normal vitamin D levels, our probiotic contributes to optimal immune system function in healthy people.
OPTIMAL PLANT STEROLS:
Microbiome Plus+ Lactobacillus Reuteri NCIMB 30242 helps maintain already normal plant sterol levels. Normal plant sterols levels contribute to heart health, normal red blood cell levels, and hormonal balance.
BOWEL MOVEMENTS
Our probiotic works with your gut to encourage healthy bowel movements, optimal bowel function, and passage of stools. By helping maintain a strong intestinal lining, Microbiome Plus+ Lactobacillus Reuteri NCIMB 30242 supports the body in preventing harmful organisms from crossing from the gut into the bloodstream.
MOOD, ENERGY & WELL-BEING
A healthy gut microbiome supports nutrient absorption, general wellbeing, mood, and cognitive function. Fatigue, irritability, and poor motivation may be signs of a nutrient deficiency. Please discuss your symptoms with your doctor. Probiotics encourage the development of a healthy microbiome and optimize nutrient breakdown and absorption.
When it comes to the health effects and quality of our products, we leave no room for guessing.
Microbiome Plus+ probiotics are manufactured in GMP-certified US facilities, rooted in science, and backed by many clinical trials (Read the studies here: Jones et al., 2011, Jones & Prakash, 2012; Jones et al., 2013, Jones et al., 2013; Martoni et al., 2015; Jones et al., 2011; Jones et al, 2012).
Product Description
✔ TRUSTED PROBIOTIC: Our well-researched formula is recommended by doctors for a reason. It’s among the few probiotic supplements clinically proven to support digestive health.*
✔ #1 PROBIOTIC FOR HEART AND IMMUNE SUPPORT: Award-winning, heart-healthy probiotic. Clinically researched for supporting already normal vitamin D, LDL cholesterol, total cholesterol, C-reactive protein, and fibrinogen levels—factors that promote cardiovascular and immune health. Each capsule contains 3.5 billion CFU and starts acting only once it reaches your colon.*
✔ GRAS: Our L. reuteri NCIMB 30242 is among the few probiotic strains granted Generally Recognized As Safe (GRAS) status by the U.S. Food and Drug Administration. It’s suitable for adult men and women of all ages.
* These statements have not been evaluated by the U.S. Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Please consult your physician before implementing any new diet, exercise, and dietary supplement programs, especially if you have preexisting medical conditions or are taking prescribed medications.
Your Overall Health

HEART HEALTH
Microbiome Plus+ L. reuteri NCIMB 30242 is the #1 probiotic strain for supporting normal cholesterol, heart, and blood vessel health.

ADVANCED GUT SUPPORT
Our probiotic has clinical research to back up its effects on the gut. It helps maintain a healthy gut microbiome, which supports your digestion, well-being, mood, energy levels, and longevity.

IMMUNE BALANCE
Microbiome Plus+ L. reuteri NCIMB 30242 helps maintain a healthy immune system response and already normal vitamin D levels.
Groundbreaking Probiotics To Support General Health
Microbiome Plus L. reuteri NCIMB 30242 probiotics have been created to enhance general well-being in both men and women. You know exactly what you’re getting. No need to experiment with untested mixtures and dosages of dozens of probiotic strains.
A Science-Based Lactobacillus Supplement
✔ 7 BILLION CFU DAILY DOSE: taken as two capsules per day, formulated to restore gut microbiome balance.
✔ 28-days supply in one bottle
✔ NO REFRIGERATION REQUIRED: Our probiotic is 100% shelf life stable, designed for survivability. No need to keep it in the fridge—you can take it with you wherever you go. It provides live bacteria until the expiry date.
✔ NO HISTAMINE RELEASE: Unlike many other strains, L. reuteri NCIMB 30242 didn’t release biogenic amines like histamine, tyramine, putrescine, and cadaverine in lab tests.
✔ FREE OF ALLERGENS: Our probiotic doesn’t contain gluten, soy, corn, milk, egg, wheat, peanuts, shellfish, or preservatives.
✔ VEGAN and NON-GMO, from renewable and sustainable sources.
✔ DEVELOPED BY DOCTORS AND SCIENTISTS, extensively tested in cellular and clinical studies.
✔ MADE IN USA, manufactured in facilities following Good Manufacturing Practice (GMP) standards.
✔ THIRD-PARTY TESTED: Our award-winning probiotic supplements are routinely third-party tested for potency, heavy metals, and micros. When you purchase our products, you know you’re getting a safe, effective, clean formulation.
More Information
- Do Microbiome Plus+ probiotics need to be refrigerated?
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What are the ingredients in the prebiotic and probiotic supplements?
PROBIOTIC CAPSULE INGREDIENTS:
Lactobacillus reuteri NCIMB 30242 3.5 billion CFU per capsule.Other ingredients: microcrystalline cellulose, silicon dioxide, magnesium stearate, vegetable capsule (hypromellose, titanium dioxide).
PREBIOTIC TABLET INGREDIENTS:
scFOS (Short-chain fructooligosaccharides) 600mg per tablet.Other Ingredients: microcrystalline cellulose, dicalcium phosphate, stearic acid, magnesium stearate, croscarmellose sodium and silicon dioxide.
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Does this product contain scFOS?
Onlu our prebiotic tablets contain scFOS.
Our probiotic capsules do not contain scFOS.
Other products do not contain scFOS.
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Should I take the combo or the probiotic only?
Our Microbiome Plus+ Gastrointestinal Combo (Probiotic L. Reuteri NCIMB 30242 & Prebiotic scFOS Fiber) may be more suitable for people who don’t have an issue with FODMAPs. Prebiotics act in synergy with probiotics.
The probiotic without the combo (Microbiome Plus+ Lactobacillus Reuteri NCIMB 30242) is without short-chain fructooligosaccharides (scFOS).
The probiotic included in our combo was researched in people with IBS, so it’s considered to be “IBS safe.”
Nonetheless, FODMAPs tend to cause problems in some people with irritable bowel syndrome (IBS).
The probiotic only (without the prebiotic) may be more suitable for people who don’t tolerate FODMAPs (fermentable oligo-, di-, mono-saccharides and polyols).
Microbiome Plus+ Prebiotic scFOS Fiber is also available as a separate product. You can try adding it to the probiotic if you’re not sure what’s right for you.
If you have IBS or don’t tolerate FODMAPs, please talk to a doctor. Have in mind that this product is not a treatment for your condition.
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Why do Microbiome Plus+ probiotics contain hydroxypropyl methylcellulose (HPMC)?
Hydroxypropyl methylcellulose (HPMC) is a food-grade, plant-based polymer. It’s used to encapsulate the probiotic in a vegan delayed-release capsule. This innovative technology helps live probiotics in our formulation resist stomach acid and reach the colon. Without HPMC, live probiotics would be killed by stomach acid.
Read more about our delayed-release technology here.
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Why do Microbiome Plus+ probiotics contain gellan gum? Is gellan gum safe?
Gellan gum is used as part of our microencapsulation technology. It’s added to enhance the viability of probiotics.
Gellan gum has been thoroughly researched for enhancing the delivery of live probiotics in various formulations. Please look up “Microencapsulation Improved Probiotics Survival During Gastric Transit.”
Gellan gum has been extensively studied, tested, and proven to be safe for use in food for over 30 years. Scientists even tested the safety of gellan gum mega doses that would never be used in food (pounds in one meal) and concluded that it was non-toxic.
Gellan gum is made using bacteria found in nature to ferment nutrients. It’s commonly added to many foods in small amounts (to create gels and add texture).
As with many components of food, such as lactose or gluten, some people may have individual or unique sensitivities.
The amount of gellan gum in our probiotic formulation is lower than that found in common foods.
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Do Microbiome Plus+ probiotics contain live cultures?
Yes, our probiotics contain live cultures. They are third-party tested for quality.
Each capsule contains 3.5×10⁹ CFU of Lactobacillus Reuteri NCIMB 30242.
Independent peer-reviewed research has also validated this.
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Can I ferment milk with this probiotic?
This is possible, but you would need to follow careful steps to start the fermentation process.
If you tried adding probiotic powder to milk and didn’t see any change, it’s not because the product doesn’t contain live bacteria. Not all Lactobacillus probiotics grow in milk the same way, and there are various scientific studies dedicated to the topic.
Our strain was specifically selected, developed, and grown in the lab without milk. That means it may need time to adapt to a dairy environment. Scientists tested this out. They showed that Lactobacillus reuteri NCIMB 30242 can ferment milk along with a yogurt starter, but its growth was limited.
For this reason, we recommend taking our probiotics as capsules. This ensures that you’ll get the dosage and formulation that was clinically researched.
But if you’re really into yogurt making, give this topic some in-depth research. You may want to Google “how to make lactobacillus reuteri yogurt” and run your own experiments. We can’t guarantee any results.
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Who can benefit from Microbiome Plus+ probiotics?
Our prebiotic and probiotics are a good choice for adults looking to naturally support digestion, colon health, and LDL and total cholesterol levels that are already within the normal range.
Also, healthy people who are looking to maintain immune health and vitamin D levels that are already in the normal range may benefit from our combo or standalone probiotic.
Microbiome Plus+ probiotics are meant for both men and women who want to support their gut microbiome, weight management, nutrient balance along with a healthy diet, and overall well-being.
The synbiotic combination in our formula is safe for most people with IBS, but check with your doctor if you’re not sure.
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Is this product safe for everyone?
Microbiome Plus+ Lactobacillus Reuteri NCIMB 30242 and scFOS are safe to consume daily for most people. Our probiotic has been granted Recognized as Safe (GRAS) status by the U.S. Food and Drug Administration.
L. reuteri probiotics have a long history of safe use in traditional fermented foods.
Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any other dietary supplement. Do not take this supplement if you are allergic to any of the listed ingredients.
These statements have not been evaluated by the U.S. Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.