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  • Organic Ashwagandha
  • Bone & Mind
  • High Potency Vitamin D3
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About This Product

  • Details
  • Science
  • Benefits
  • FAQ

Ingredients

All ingredients are sourced from renewable and sustainable sources

Probiotic Ingredients

Lactobacillus Reuteri NCIMB 30242

3.5 Billion AFU/capsule

Our primary ingredient is our unique probiotic strain which has been through rigorous clinical trials performed by independent labs and researchers and published in 7 peer-reviewed scientific papers

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Other Ingredients

In each capsule:

  • Microcrystalline cellulose
  • Silicone dioxide
  • Magnesium stearate
  • Vegetable capsule (hypromellose, titanium dioxide)

Probiotic Ingredients

600mg/tablet

600mg/tablet

Short-chain fructooligosaccharides (scFOS) are natural dietary fibers that belong to the fructans family and are proven to aid in healthy bacterial growth and prevent the colonization and growth of pathogenic gut bacteria.

Other Ingredients

In each capsule:

  • Microcrystalline cellulose
  • Dicalcium phosphate
  • Stearic acid
  • Magnesium stearate
  • Croscarmellose sodium
  • Silicon dioxide

Product Description

Complete Stress, Sleep & Mood Support Protocol

Buy all 3 together and save 20%!

Chronic stress, disrupted sleep, and low mood form a self-reinforcing cycle. This protocol breaks that cycle at three critical points: cortisol regulation, neurotransmitter support, and foundational hormonal balance.

What's Included

  • Organic Ashwagandha — The gold-standard adaptogen for stress. Clinically shown to significantly reduce cortisol levels, helping your body return to calm from the inside out. Organic, with standardized withanolide content for consistent potency.
  • Bone & Mind (Calcium + 5-HTP) — 5-HTP is the direct precursor to serotonin and melatonin — the neurotransmitters that regulate mood, emotional balance, and sleep cycles. Paired with calcium for bone health and nervous system support.
  • High Potency Vitamin D3 (2,000 IU) — Vitamin D deficiency is directly linked to low mood, anxiety, and poor sleep quality. Over 40% of adults are deficient. 2,000 IU supports optimal serotonin synthesis and immune balance.

Why This Combination Works

Ashwagandha lowers the cortisol that keeps you wired at night. 5-HTP builds the serotonin and melatonin that help you sleep deeply and wake up in good spirits. Vitamin D3 provides the hormonal foundation both systems need to function properly. Taken consistently, this trio resets your stress-sleep-mood cycle.

Retail Value: $53.97 — Bundle Price: $43.18 (Save $10.79)

  • When to Use
  • How to Use

Take one capsule twice daily with meals or as directed by a physician.

Take one capsule twice daily with meals

Microbiome Plus+ Compared to Other Probiotics

Microbiome Plus+ L. reuteri NCIMB 30242

Brand A

Brand B

Clinically researched strain

✔

✔

✘

GRAS status

✔

✔

✘

CFU count per strain per capsule

3.5B

0.2B

1.2B

Acid-resistant capsule

✔

✘

✔

Designed for survivability

✔

✔

✘

Free of dairy, gluten, and soy

✔

✔

✔

Shelf-stable bottle

✔

✘

✔

Supports already healthy vitamin D levels

✔

✘

✘

Supports already normal cholesterol

✔

✘

✘

Encourages gut microbiome diversity

✔

✔

✔

Histamine-release free

✔

✘

✘

FODMAPs free

✔

✔

✘

What is Microbiome Plus?

Backed By Science

Our L. Reuteri NCIMB 30242 probiotic and scFOS prebiotic fiber is a digestive aid and it  contributes to your well-being. 

  • Supports gut health, good digestion
  • Supports healthy LDL cholesterol already within the normal range
  • Keeps already normal vitamin D levels in check
  • Supports cardiovascular health by encouraging already normal levels of CRP, fibrinogen, plant sterols, and apolipoprotein B-100
  • Supports microbiome diversity in IBS
  • Safe and well-tolerated
  • Well-researched prebiotic fiber for adults

Probiotics For Cholesterol, Recommended By Doctors

"I have been using MicroBiome Plus for several years. It has greatly benefitted my patients with gut problems and those with cardio metabolic issues as well.

— Dr. Deanna M. Cherrone, Natural Health and Healing Clinic

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Benefits

Improve Heart Health

The oral supplement, lactobacillus reuteri NCIMB 30242, is an award-winning, heart-healthy probiotic. L reuteri is clinically researched for supporting already normal LDL cholesterol, total cholesterol, C-reactive protein, and fibrinogen levels—factors that promote cardiovascular health.* L. reuteri benefits also support healthy gut microbiome diversity.

Maintain Healthy Gut Microbiome

Lactobacillus reuteri benefits also include an increase in mucin production. Mucin lines your gut, helping to protect your gut lining, repair any damage, and in general, to maintain a healthy gut microbiome.

Maintain Healthy Vitamin D Levels

It has been hypothesized that Lactobacillus reuteri NCIMB 30242 may help raise vitamin D levels in two ways. One such way is to boost lactic production in your gut. Lactic production can help absorb vitamin D. L reuteri can also help because it increases the production of 7-DHC — a compound that can be turned into vitamin D by your liver.

Lower Cholesterol

Lactobacillus reuteri NCIMB 30242 improves your heart health by lowering LDL cholesterol levels and improving your vitamin D production. Having and maintaining good cholesterol levels is integral for your health. The benefits of our Microbiome Plus L. reuteri NCIMB 30242 strain is backed by clinical studies and scientific research.

L. reuteri NCIMB 30242 has an enzyme called bile salt hydrolase (BSH). BSH helps to set bile acids free in a method known as deconjugating. Free bile acids reduce the body’s absorption of cholesterol in your gut by binding to the cholesterol, allowing elimination. Your liver then increases the production of new bile acids and your body subsequently breaks down more cholesterol.

Superior Quality

OurL. reuteri Our L. reuteri probiotic is backed by clinical trial results published in 7 peer-reviewed scientific studies. Each capsule contains 3.5 billion CFU and starts acting only once it reaches your colon. No surprises, just science.*

✔ GRAS: Our L. reuteri NCIMB 30242 is among the few probiotic strains granted Generally Recognized As Safe (GRAS) status by the U.S. Food and Drug Administration. It’s suitable for adult men and women of all ages.

Your Overall Health

HEART HEALTH

Microbiome Plus+ L. reuteri NCIMB 30242 is the #1 probiotic strain for supporting normal cholesterol, heart, and blood vessel health.

IMMUNE BALANCE

Our probiotic helps maintain a healthy immune system response and already normal vitamin D levels.

ADVANCED GUT SUPPORT

Microbiome Plus+ L. reuteri NCIMB 30242 has clinical research to back up its effects on the gut. It helps maintain a healthy gut microbiome, which supports your digestion, well-being, mood, energy levels, and longevity.

Groundbreaking Probiotics To Support General Health

DIGESTIVE FUNCTION IS CRUCIAL FOR HEALTH — Microbiome Plus+ Gastrointestinal Probiotics supports the digestive function required for wellbeing and longevity. Good bacteria are necessary for nutrient absorption, reducing harmful pathogens and to aid healing.

Microbiome Plus L. reuteri NCIMB 30242 probiotics have been created to enhance general well-being in both men and women. You know exactly what you’re getting. No need to experiment with untested mixtures and dosages of dozens of probiotic strains. 

Promotes Overall Health

IMMUNE FUNCTION — Microbiome Plus+ Gastrointestinal Probiotics helps to support a healthy immune functions. 


HEALTHY BILE METABOLISM — Probiotics enhance and maintain a healthy microbiome and optimal bile metabolism.


SUPPORTS OVERALL HEALTH — Microbiome Plus+ Gastrointestinal Probiotics are well researched and well loved. It’s time you discover their profound benefits for overall health, too!

Faq's

Do Microbiome Plus+ probiotics need to be refrigerated?
No. Our probiotics are shelf stable and don’t need to be kept in the fridge.
What are the ingredients in this product?
Lactobacillus reuteri NCIMB 30242 3.5 billion CFU per capsule. Other ingredients: microcrystalline cellulose, silicon dioxide, magnesium stearate, vegetable capsule (hypromellose, titanium dioxide).
Does this product contain scFOS?
No, Microbiome Plus+ Lactobacillus Reuteri NCIMB 30242 does NOT contain scFOS.
Should I take this product or the gastrointestinal combo?
Microbiome Plus+ Lactobacillus Reuteri NCIMB 30242 is without short-chain fructo-oligosaccharides (scFOS). This product may be more suitable for people who don’t tolerate FODMAPs (fermentable oligo-, di-, mono-saccharides and polyols). FODMAPs tend to cause problems in some people with irritable bowel syndrome (IBS). Our Microbiome Plus+ Gastrointestinal Combo (Probiotic L. Reuteri NCIMB 30242 & Prebiotic scFOS Fiber) can be purchased here. The combo may be more suitable for people who don’t have an issue with FODMAPs. Prebiotics act in synergy with probiotics. Microbiome Plus+ Prebiotic scFOS Fiber is also available as a separate product here. You can try adding it to the probiotic any time if you’re not sure what’s right for you.
Why do Microbiome Plus+ probiotics contain hydroxypropyl methylcellulose (HPMC)?
Hydroxypropyl methylcellulose (HPMC) is a food-grade, plant-based polymer. It’s used to encapsulate the probiotic in a vegan delayed-release capsule. This innovative technology helps live probiotics in our formulation resist stomach acid and reach the colon. Without HPMC, live probiotics would be killed by stomach acid.Read more about our delayed-release technology here.
Why do Microbiome Plus+ probiotics contain gellan gum? Is gellan gum safe?
Gellan gum is used as part of our microencapsulation technology. It’s added to enhance the viability of probiotics.Gellan gum has been thoroughly researched for enhancing the delivery of live probiotics in various formulations. Please look up “Microencapsulation Improved Probiotics Survival During Gastric Transit.”Gellan gum has been extensively studied, tested, and proven to be safe for use in food for over 30 years. Scientists even tested the safety of gellan gum mega doses that would never be used in food (pounds in one meal) and concluded that it was non-toxic.Gellan gum is made using bacteria found in nature to ferment nutrients. It’s commonly added to many foods in small amounts (to create gels and add texture).As with many components of food, such as lactose or gluten, some people may have individual or unique sensitivities.The amount of gellan gum in our probiotic formulation is lower than that found in common foods.
Do Microbiome Plus+ probiotics contain live cultures?
Yes, our probiotics contain live cultures. They are third-party tested for quality.Each capsule contains 3.5×10⁹ CFU of Lactobacillus Reuteri NCIMB 30242.Independent peer-reviewed research has also validated this.
Can I grow milk with this probiotic?
This is possible, but you would need to follow careful steps to start the fermentation process.If you tried adding probiotic powder to milk and didn’t see any change, it’s not because the product doesn’t contain live bacteria. Not all Lactobacillus probiotics grow in milk the same way, and there are various scientific studies dedicated to the topic.Our strain was specifically selected, developed, and grown in the lab without milk. That means it may need time to adapt to a dairy environment. Scientists tested this out. They showed that Lactobacillus reuteri NCIMB 30242 can ferment milk along with a yogurt starter, but its growth was limited.For this reason, we recommend taking our probiotic as capsules. This ensures that you’ll get the dosage and formulation that was clinically researched.But if you’re really into yogurt making, give this topic some in-depth research. You may want to Google “how to make lactobacillus reuteri yogurt” and run your own experiments. We can’t guarantee any results.
Who Can Benefit from Microbiome Plus+ Lactobacillus Reuteri NCIMB 30242?
Our probiotic is a good choice for adults looking to naturally support healthy LDL and total cholesterol levels that are already within the normal range.Also, healthy people who like the digestive benefits of probiotics and are also looking to maintain immune health and vitamin D levels that are already in the normal range may benefit from Microbiome Plus+ Lactobacillus reuteri NCIMB 30242.Microbiome Plus+ probiotics are meant for both men and women who want to support their gut microbiome and overall health and well-being.
Is this product safe for everyone?
Microbiome Plus+ Lactobacillus Reuteri NCIMB 30242 is safe to consume daily for most people. Our probiotic has been granted Generally Recognized as Safe (GRAS) status by the U.S. Food and Drug Administration.L. reuteri probiotics have a long history of safe use in traditional fermented foods.Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any other dietary supplement. Do not take this supplement if you are allergic to any of the listed ingredients.